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KMID : 1007520230320142093
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Food Science and Biotechnology
2023 Volume.32 No. 14 p.2093 ~ p.2104
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Microbiota regulation by different Akebia trifoliata fruit juices upon human fecal fermentation in vitro
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Yuhao Sun
Yaru Hu
Danqi Hu
Zhuqian Xiao
Hongpeng Wang
Jun Huang
Jianwei Mao
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Abstract
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Three different Akebia trifoliata fruit juices were prepared, and their effects on modulation of human fecal microbiota were elucidated through an anaerobic fermentation in vitro. Results indicated that the introduction of inoculatedly-fermented Akebia trifoliata fruit juice promoted short-chain fatty acids productivity. Fecal microbiota analysis demonstrated up-regulations for abundances of Limosilactobacillus, Megamonas, Bifidobacterium, and Escherichia_Shigella, and down-regulations for numbers of Bacteroides, Prevotella_9, Parasutterella, and Sutterella. Correlation analysis confirmed relationships among sample components, short-chain fatty acids productivity, and microbial abundances, suggesting that sugars and organic acids stimulated growth of Actinobacteriota and suppressed proliferation of Proteobacteria, thus uncovering the underlying mechanism for the better ability of inoculatedly-fermented Akebia trifoliata fruit juice to regulate microbiota structure. Besides, clusters of orthologous groups of proteins analysis indicated that metabolite biosynthesis, energy metabolism, homeostasis maintenance and other physiological functions were ameliorated.
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KEYWORD
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Akebia trifoliata fruit, Fermented juice, Fecal microbiota, Anaerobic fermentation
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